This challenge is closed

Ophthalmology Innovation Challenge & Pilot Program

We are looking for cutting edge solutions for ophthalmology patients!

The Challenge is closed for submissions. View winner and finalists below.

Partners

In collaboration with

Roche, Start-Up Nation Central & Beilinson Hospital share a common vision of providing enhanced digital health solutions that will significantly improve retina patients’ lives and support their caregivers by enabling monitoring, enhancing patient support, and optimizing screening & diagnosis.

The Roche for a Better Future Ophthalmology Innovation Challenge & Pilot Program is a groundbreaking platform that will enable you to conduct a real-life pilot in Beilinson Hospital to test your solution. You will enjoy full support, including access to a multidisciplinary team of leading experts that will assess your solution, a comprehensive mentorship package, a fast-track for submission to the Helsinki Committee and global exposure.

The Winner

Winner

Notal Vision is a commercial stage patient-centric digital healthcare provider of remote monitoring services that extends age-related macular degeneration (AMD) monitoring from the clinic to the home, providing eye care professionals with remote diagnostic tools to support their patient care. With a proven approach to home-based, self-operated diagnostics, AI-enabled data analysis, and patient engagement services, Notal Vision helps to preserve patients’ vision long-term. The Home OCT pipeline platform developed at the company’s Tel Aviv Technology Center will support personalized treatment by monitoring disease activity and treatment response remotely, reducing office visits burden on patients and caregivers and promoting therapy adherence.

The Finalists

AEYE Health is a venture-backed digital health startup that develops AI algorithms for autonomous interpretation of fundus images for various ocular and systemic conditions. Its flagship product, AEYE DS, is an FDA-cleared algorithm for the diagnosis of diabetic retinopathy.

Its products put the power of retinal screenings in the hands of primary care physicians, enabling early detection for the prevention of vision-threatening complications.

BioT Medical, a leader in cloud-powered medical devices, has partnered with Zilia, a medical technology company specializing in non-invasive ocular biomarker measurement. This strategic alliance combines BioT’s expertise in connecting devices with healthcare systems and Zilia’s advanced ocular oximetry technology. Aimed at revolutionizing retinal disease management and patient care, the partnership focuses on early detection, personalized treatment, and continuous monitoring. By integrating spectroscopy, imaging, artificial intelligence, and seamless data communication, this collaboration seeks to enhance healthcare delivery, making it more efficient, accessible, and tailored to individual needs in the field of ophthalmology.

GistMD is an AI-based patient education and engagement platform that empowers patients and drives adherence along their care journey. By providing personalized content and behavioral change tools, GistMD achieves patient activation that leads to improved health outcomes. Personalization includes language, gender, age, culture, medical background, medication, behavioral factors and more. GistMD is deployed in numerous healthcare centers and hospitals, showing evidence-based results in improved adherence, operational efficiency, reduced staff burnout and patient satisfaction.

The CASMIP Laboratory at the School of Computer Science and Engineering, the Hebrew University of Jerusalem, and the Hadassah University Medical Center have jointly developed a novel AI-based solution for the accurate diagnosis of Inherited Retinal Dystrophies based on optical images. The solution, based on novel methods for deep-learning image processing, will assist in the early diagnosis of patients and in screening prior to genetic testing. It will also support diagnosis in locations where genetic testing is unavailable or not routinely performed. The technology holds promise for the diagnosis of other types of retinal diseases.

XOLTAR develops AI companions that emulate the one-on-one interactions nurses have with patients, guiding individuals in maintaining the healthy habits necessary to manage their medical conditions. XOLTAR implements evidence-based protocols through free-guided conversations conducted over telehealth calls. These conversations are truthful, grounded and aligned, yet provide a seamless and free-flowing patient experience. This staff-augmentation solution enhances support teams with AI companions capable of acting as co-pilots. They replicate support protocols, connect to the CRM and extend the support staff, while generating insights from video data at unlimited scale with 24/7 accessibility.

What Will You Gain From The Program?

Access and exposure to a network of Roche global experts

A special session with the Israel Innovation Authority

Investment opportunities for your company - the program will be widely globally communicated and promoted by Startup Nation Central

The Winner will implement a one-of-a-kind real-life pilot in Beilinson Hospital, with a fast track for submission to Helsinki Committee

Pilot funding - up to 200,000 NIS

(VAT included, subject to the program’s Official Rules)

50,000 NIS for pilot preparation

Up to 150,000 NIS for conducting a pilot at the Retina Unit, Beilinson Hospital

Comprehensive mentorship package

3 mentorship hours with a medical expert from the Retina Unit, Beilinson Hospital

3 additional mentorship hours with experts from Beilinson Hospital, including a fast track for submission to the Helsinki Committee

3 mentorship hours with Dr. Irit Yaniv, Co-founder and CEO, Almeda Ventures

The Challenge

Roche for a Better Future seeks innovative digital health solutions for Ophthalmology patients with retinal diseases (AMD, DME, DR & RVO), aiming to enhance support for patients and caregivers.

Areas of focus:

Follow-up & monitoring

For example: Remote monitoring of visual acuity or OCT in retinal patients; insights generation - analyzing patient data (text and imaging) to predict progression of retinal diseases.

Patient support & awareness

For example: Disease management optimization, patient adherence to treatment regimen and patient awareness.

Detection optimization

For example: Screening patients with high risk for retinal diseases and diagnosis of retinal diseases.

Additional Considerations

We welcome solutions with a Technology Readiness Level (TRL) of 5 and above.
Solutions should be compatible for a pilot at Beilinson Hospital of Clalit Health Services.
Preference will be given to solutions addressing the first two areas of focus (i.e. follow-up & monitoring, and patient support & awareness).
Good solutions will address at least one of these areas of focus, while great solutions will tackle more than one including infrastructure technologies.
We will prioritize technologies and digital health solutions that are able to integrate to the Electronic Medical Records (EMR), based on FHIR.

Timeline of the Challenge

14.9.23
Applications open
31.12.23
Applications close
13.2.24
Finalists notification
28.2.24
Finalists Pitch to Advisory Committee
4.3.24
Global showcase event with the finalists. View recording!

Advisory Committee

About Retinal Diseases

Retinal diseases are a major cause of visual impairment and blindness, especially among older individuals and diabetic patients. The prevalence of these diseases is increasing due to aging populations and the global rise in diabetes. There is a growing need for better treatments and enhanced digital health solutions to support patients in preserving their vision so that they can witness the most precious moments in life with their loved ones.

Digital health may offer promising solutions to reduce clinic visits, improve treatment adherence, enable personalized care and optimize the management of retinal diseases, leading to better patient outcomes, reduced healthcare burden and enhanced well being.

 

Partners

In Collaboration with

Founded in 1896 in Basel, Switzerland, as one of the first industrial manufacturers of branded medicines, Roche has grown into the world’s largest biotechnology company and the global leader in in-vitro diagnostics. The company pursues scientific excellence to discover and develop medicines and diagnostics for improving and saving the lives of people around the world. We are a pioneer in personalised healthcare and want to further transform how healthcare is delivered to have an even greater impact. To provide the best care for each person we partner with many stakeholders and combine our strengths in Diagnostics and Pharma with data insights from the clinical practice.

For more information, please visit www.roche.com.

Startup Nation Central is a free-acting NGO providing global solution seekers frictionless access to Israel’s bold and impatient innovators to help tackle the world’s most pressing challenges.

For more information, please visit: www.startupnationcentral.org

The Jusidman Cancer Center at Sheba Medical Center in Israel is a globally renowned facility specializing in innovative cancer treatment. It provides advanced diagnostic tools and therapies, including immunotherapy, targeted therapy, and personalized medicine, delivered through a multidisciplinary approach. Known for its innovation, the center uses cutting-edge technologies like robotic systems and modern radiation therapies for precise and effective treatments, while serving as a hub for groundbreaking oncology research.

Beyond medical care, the Jusidman Cancer Center emphasizes holistic support, offering mental health services, rehabilitation programs, and palliative care to enhance patients’ well-being. By combining clinical excellence, advanced research, and personalized care, the center has established itself as a leader in oncology, providing world-class treatment in a compassionate and patient-focused environment.

https://www.shebaonline.org/department/cancer-treatment-in-israel-the-cancer-center/

ARC Oncology is dedicated to advancing progress in the following key areas: fostering innovation through both organic development and collaborations with companies of all sizes, transforming operational processes, business development and harnessing real-world evidence data.

Central to our efforts is ‘OncoMind’—a state-of-the-art data laboratory that integrates comprehensive clinical information, treatment histories, genetic sequencing data, pathological insights, and more from patients across all our centers. This advanced infrastructure enables AI-driven research aimed at improving patient outcomes and shaping the future of oncology.

Together, these initiatives empower us to continuously advance cancer research and elevate patient care.

ARC (Accelerate, Redesign, Collaborate), the innovation arm of Sheba Medical Center, founded and directed by Prof. Eyal Zimlichman, is shaping the future of medical innovation by connecting entrepreneurs and clinicians, advancing the development and implementation of new technologies, and creating breakthrough economic frameworks in healthcare. ARC’s unique model, the first of its kind in global healthcare, has evolved into a global blueprint, with a network of innovation centers in leading hospitals and research institutions across London, Melbourne, Singapore, Berlin, and New Zealand. ARC’s global network promotes technology-based medical solutions and accelerates the adoption of innovation within health systems worldwide.

ARC Sheba provides startups and researchers with exclusive access to Sheba’s core assets, clinical data and medical talent, while advancing the hospital’s vision to serve as a global hub for AI-driven medicine. Led by Avner Halperin, the model’s success has already led to exits totaling approximately $1 billion, with profits reinvested to further accelerate Sheba’s AI and data revolution.

Learn more about ARC at: https://arcinnovation.org/

8400 The Health Network accelerates growth in Israel’s health tech sector by bringing together key stakeholders to foster innovation and bridge gaps in the ecosystem.

For more information, please visit: https://www.8400thn.org/.